- These cholesterol conjugates provide us with a very flexible ‘tool-box’ that can be used to tether phospholipid bilayers to surfaces, to join bilayers together (bilayer-to-bilayer, bilayer-to-vesicle, vesicle-to-vesicle, etc.) or to anchor molecules, biomolecules, macromolecules or particulate species to the surface of the bilayer.
- From these data, plots of the lateral compressibility, χ, as a function of lateral lipid density (a-1) and of the thermal expansion coefficient, α, as a function of temperature (T) were obtained.
- The combination of the PLE with a small molecule chemotherapeutic is known as a Phospholipid Drug Conjugate or PDC™. PDCs provide targeted delivery and release of therapeutic payloads inside ...
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